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Home - Products - GPCR/G Protein - Antibacterial - Azlocillin sodium

Azlocillin sodium

CAS No. 37091-65-9

Azlocillin sodium( Azlocillin sodium salt | Sodium Azlocillin | Securopen | Bay-e 6905 | Azlocillin )

Catalog No. M14277 CAS No. 37091-65-9

Azlocillin is an acylampicillin with a broad spectrum against bacteria.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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200MG 27 In Stock
500MG 43 In Stock
1G 73 In Stock
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Biological Information

  • Product Name
    Azlocillin sodium
  • Note
    Research use only, not for human use.
  • Brief Description
    Azlocillin is an acylampicillin with a broad spectrum against bacteria.
  • Description
    Azlocillin is an acylampicillin with a broad spectrum against bacteria.(In Vitro):Over 75% of the isolates of Pseudomonas aeruginosa are inhibited by Azlocillin at a concentration of 12.5 μg/mL. Azlocillin is also active against indole-negative and -positive Proteus spp., inhibiting 98% and 71%, respectively, at a concentration of 12.5 μg/mL. Gram-positive cocci except penicillin G-resistant Staphylococcus aureus are susceptible to Azlocillin.(In Vivo):Azlocillin (75 mg/kg) treatment increases the survival of neutropenic mice infected with Escherichia coli or Klebsiella pneumoniae.
  • In Vitro
    Over 75% of the isolates of Pseudomonas aeruginosa are inhibited by Azlocillin at a concentration of 12.5 μg/mL. Azlocillin is also active against indole-negative and -positive Proteus spp., inhibiting 98% and 71%, respectively, at a concentration of 12.5 μg/mL. Gram-positive cocci except penicillin G-resistant Staphylococcus aureus are susceptible to Azlocillin.
  • In Vivo
    Azlocillin (75 mg/kg) treatment increases the survival of neutropenic mice infected with Escherichia coli or Klebsiella pneumoniae.
  • Synonyms
    Azlocillin sodium salt | Sodium Azlocillin | Securopen | Bay-e 6905 | Azlocillin
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    PBPs
  • Research Area
    Infection
  • Indication
    ——

Chemical Information

  • CAS Number
    37091-65-9
  • Formula Weight
    483.47
  • Molecular Formula
    C20H22N5NaO6S
  • Purity
    >98% (HPLC)
  • Solubility
    Ethanol: 3 mg/mL (6.19 mM); Water: 97 mg/mL (200.21 mM); DMSO: 97 mg/mL (200.21 mM)
  • SMILES
    O=C([C@@H](C(C)(C)S[C@]1([H])[C@@H]2NC([C@H](NC(N3CCNC3=O)=O)C4=CC=CC=C4)=O)N1C2=O)[O-].[Na+]
  • Chemical Name
    (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[[(2R)-2-[(2-oxoimidazolidine-1-carbonyl)amino]-2-phenylacetyl]amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid sodium

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Stewart D, et al. Antimicrob Agents ChemOthers, 1977, 11(5), 865-870.
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